Were it not for our large brains, we humans would surely have died out long ago. Not physically equipped to match the speed and strength of African predators, we would never have left that Continent.
As it turned out, our large brains came to the rescue and we eventually spread across the globe. In concert, the sophistication of our varied cultures increased and the Industrial and Technological Revolutions assured that we would take control of the planet, leading to both good and bad consequences. Indeed, we may yet facilitate our own extinction.
Throughout this history, intellectual endeavors were challenged by mysticism and political expediency in their various forms. It is imperative that we trust our intelligence and the scientific method that we learned to utilize in order to survive and thrive. Modern efforts to ignore or debase science will hasten our demise; unfortunately, we will take most other species with us.