We humans are social creatures and even though some of us cherish (if not require) periods of solitude, our lives are defined by a long series of relationships. Indeed, an inability to form and sustain relationships, usually due to psychological or psychiatric problems, leads to social dysfunction and, in extreme cases, severe depression and suicide.
Of course, there is a hierarchy of relationships in our lives, reflected by the degree of influence that they have. Partners, family members, close friends and past lovers are certainly high on that list but mentors, teachers, colleagues and even casual relationships impact our lives. It is no surprise that novels, movies, plays and stories that focus on human relationships tend to be most acclaimed.
There are some individuals who choose the hermit's life, swearing off the importance of others. But they likely fall into the group mentioned above, having endured an abusive childhood or an especially painful loss. For the rest of us, relationships are vital to our welfare, even those that may not end in storybook fashion.